Friday, November 30, 2012

Astronomy and Space Sticker Book | Education & Reference | paribsa

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Source: http://abrasiveness-draconian.blogspot.com/2012/11/astronomy-and-space-sticker-book.html

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Analysis: Palestinian statehood vote a personal victory for Abbas

Chip East / Reuters

Mahmoud Abbas, also known as Abu Mazen, has endured top Arab leaders beating a path to his rival in Gaza, Prime Minister Ismail Haniyeh, the leader of Hamas. Hamas may not have won militarily in this month's mini-war with Israel but it paid off politically and diplomatically big-time. From pariah Hamas emerged as the power-player in Palestinian politics with a clear message: violence pays.

By Martin Fletcher, NBC News

With Palestinians looking certain to win coveted U.N. recognition as a state on Thursday, Palestinian President Mahmoud Abbas can chalk up the General Assembly vote as a personal triumph on two levels.

From his headquarters in Ramallah on the West Bank Abbas, also known as Abu Mazen,?has endured?top Arab leaders beating a path to his rival in Gaza, Prime Minister Ismail Haniyeh, the leader of Hamas. Hamas may not have won militarily in this month's mini-war with Israel but it paid off big-time, politically and diplomatically. From pariah status, Hamas emerged as the power-player in Palestinian politics with a clear message: Violence pays.


Abbas, who all his political life has preached non-violence, has recently seen his already marginalized position eroded further. All the more reason for him to have insisted on the United Nations vote, fending off objections and threats from Israel and Washington. So victory in the General Assembly sounds his own strong message: non-violence pays too.

?

Being?accepted as a non-member state, a promotion from its previous observer state, would be the Palestinians' biggest political victory. It places them on the path to full recognition as a member-state of the UN, and allows it to join UN agencies such as the International Criminal Court in The Hague.?

?Arafat's body exhumed; experts to investigate if he was poisoned

The non-member observer state status could also open the way for possible war crimes charges against ?Israel ?at the International Criminal Court.

Oliver Weiken / EPA

Israel's military said it had accomplished its objectives while Hamas claimed victory after the two sides exchanged deadly airstrikes and rocket attacks for over a week.

Another personal triumph for Abbas: For the last two years Abbas has threatened to resign, claiming he wanted a quieter life.?U.N. victory means he can say to his compatriots: I have fulfilled my promise and leave you now with this new status in international politics. Now you take the baton and run with it. He could bow out on top. That's what Palestinians in Ramallah today were saying could be?Abbas' next step.

Gazans move quickly to rebuild bombed tunnels to bring in food, weapons

Another result of success in the U.N. has already been the united voice of Palestinians today. In a rare show of unity, Hamas has joined Fatah celebrations in the West Bank and Gaza, celebrating together this?historic political moment.?

These symbolic breakthroughs for Abbas and the Palestinians It may not mean any change on the ground, though.

Arafat's exhumation: Palestinians' desire for truth might be dashed again

Initially Israel threatened that if Abbas did not call off the vote it would punish Abbas: withhold tax payments, possible annex the Jewish settlements on the West Bank and impose harsh sanctions. In the past few days that position has softened.

But Israel still insists, joined by Washington, that Abbas' U.N. gambit is no substitute for face-to-face negotiations. The road to peace does not go via the U.N. Plaza in New York but via Jerusalem and Ramallah.

Palestinians: Settlers threaten West Bank's centuries-old olive harvest tradition

And although this appears like a Palestinian victory, analysts here point out that whatever Mahmoud Abbas has achieved in the United Nations today is less than Palestinians were offered 65 years ago. Then they were offered a state in Palestine and full membership in the United Nations. Now?celebrations are about?their status as a 'non-member state'.

Martin Fletcher is the author of "The List", "Breaking News" and "Walking Israel".

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Source: http://worldnews.nbcnews.com/_news/2012/11/29/15542075-un-palestinian-statehood-vote-to-be-a-personal-political-victory-for-abbas?lite

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Xavier Dolan's "Laurence Anyways" added to Palm Springs lineup

NEW YORK (Reuters) - A young model was either insane, or a calculating, quick-thinking murderer who feigned mental illness when he killed and castrated his lover, a prominent Portuguese journalist, in their New York hotel room last year, a jury heard on Wednesday. No one disputes that Renato Seabra, 22, killed Carlos Castro, 65, in January 2011. Seabra pleaded not guilty by reason of insanity to a charge of second degree murder, and his trial reached closing arguments at Manhattan criminal court. ...

Source: http://news.yahoo.com/xavier-dolans-laurence-anyways-added-palm-springs-lineup-235041279.html

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Thursday, November 29, 2012

Inviting customer complaints can kill business

ScienceDaily (Nov. 29, 2012) ? Giving customers a chance to complain can be a bad idea if customers believe they're to blame for a product's failure, a new study from the Sauder School of Business at UBC shows.

"It's commonly assumed that giving customers a chance to voice grievances allows companies to maintain relationships," says Marketing Professor Darren Dahl, who co-authored the recent Journal of Marketing study with PhD student Lea Dunn.

"But our research shows that when a person feels implicated in a product's failure -- think building Ikea furniture -- they're more likely to shift blame to the product when complaining and increase ill will toward it."

In an experiment, subjects were divided into two groups and directed to replicate the preparation of an "award-winning smoothie." All of the participants were set-up to fail with poor quality food processors.

Half the group was made to feel the smoothie failure was their fault and the other half was told that it was likely a machine malfunction.

Participants primed to believe the failure was their fault rated the machine lower on a nine-point scale after complaining -- 3.29 -- versus the same participants who were not given the chance to complain -- 4.31.

Participants primed to blame the processor rated the device higher after given the chance to complain -- 4.02 versus 3 out of nine.

A further experiment showed that when self-blamers were provided with affirmative statements about their competence, they became more likely to rate a product favourably after complaining -- 5.22 versus 3.36 on a nine-point scale.

"With companies turning to social media to communicate with consumers, the power of customer complaints has been amplified," says Professor Dahl. "Our study shows that companies shouldn't just let people sound off. They need to be stroking egos, as well."

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The above story is reprinted from materials provided by University of British Columbia.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/mind_brain/consumer_behavior/~3/dNjEuapQ6F0/121129111837.htm

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Ironwood's constipation drug gets European approval

(Reuters) - Ironwood Pharmaceuticals Inc said its drug to treat irritable bowel syndrome with constipation has received marketing approval in Europe.

The drug linaclotide, meant for adults, will be launched in Europe in the first half of 2013 under the brand name Constella, the company said in a statement.

Constella received U.S. regulatory approval in August and Ironwood will sell the drug in the United States with its marketing partner Forest Laboratories under the brand name Linzess.

"We don't see Constella's performance in Europe as a significant value driver for Ironwood," Ladenburg Thalmann analyst Juan Sanchez wrote in a note to clients.

Sanchez estimates that Constella could bring in revenue of $189 million in 2018.

Shares of Ironwood were up 2 percent at $10.98 on the Nasdaq on Wednesday afternoon.

(Reporting by Shailesh Kuber in Bangalore; Editing by Supriya Kurane)

Source: http://news.yahoo.com/ironwoods-constipation-drug-gets-european-approval-180344990--finance.html

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Scientists uncover a novel cooperative effort to stop cancer spread

ScienceDaily (Nov. 28, 2012) ? Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.

The discovery offers a fresh batch of possible therapeutic targets as well as new diagnostic tools with the potential to predict and inhibit the spread of cancer (metastasis) in patients suffering from the disease.

The research, published recently in The Journal of Biological Chemistry, was conducted by TSRI Professor Donald G. Phinney, a nationally recognized authority in the study of adult bone marrow-derived stem cells, and a postdoctoral fellow in his laboratory, Christopher L. Haga.

In the new study, the scientists found that a cluster of seven microRNAs (miRNA) function cooperatively to repress a process known as epithelial-to-mesenchymal transition (EMT). While EMT is part of the normal biology of cell development in some parts of the body, the process has recently been implicated in two dangerous aspects of tumor growth -- tumor metastasis and the growth of drug-resistant cancer stem cells.

MicroRNAs are tiny fragments of RNA found in all mammalian cells. They bind to messenger RNAs, a process that generally results in gene silencing. This cluster of miRNAs, located in a genetic region known as DLK1-DIO3, suppresses a specific signaling network in human cancers that primarily affect glands such as breast cancer.

"These results establish the DLKI-DIO3 miRNA cluster as a critical checkpoint regulating tumor growth and metastasis," said Phinney. "Our data shows that when this cluster is silenced, it accelerates tumorogenesis and proliferation by inducing EMT."

Silencing the DLK1-DIO3 genetic region is an early event for tumors, Phinney said, pointing out that micro-metastasis can be detected even in the early stages of breast cancer.

One of the seven miRNAs highlighted in the new study -- MiR-544 -- appears to be potent in its powers of inhibition, repressing cancer cell proliferation by inducing Ataxia telangiectasia mutated (ATM), a protein involved in stopping the cell cycle once DNA damage is detected.

"What's interesting is that MiR-544 blocks cell growth in every tumor cell line we've put it into, so we're looking at it as a potential therapeutic target," Phinney said.

Phinney noted that dozens of miRNAs exist in the same genetic region. "It's possible there are other clusters that work together to affect tumor growth and metastasis," he said.

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Story Source:

The above story is reprinted from materials provided by Scripps Research Institute.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. C. L. Haga, D. G. Phinney. MicroRNAs in the imprinted DLKI-DIO3 region repress the Epithelial-to-Mesenchymal transition by targeting the TWIST1 signaling network. Journal of Biological Chemistry, 2012; DOI: 10.1074/jbc.M112.387761

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/5ge7aBPl3w0/121128122041.htm

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Wednesday, November 28, 2012

Autoliv Appoints New Head of Corporate Communications ...

| Source: Autoliv Inc.
(Stockholm, November 28, 2012) ? ? ? Autoliv Inc. ? the global leader in automotive safety systems ? has appointed Mr. Thomas J?nsson to become its Vice President of Corporate Communications.  He will replace Mr. Mats ?dman who will retire in 2013 after 18 years with the company. Mr. J?nsson, age 46, is currently Vice President of Brand and External Communications, for TeliaSonera, a position he has held since June 2010. Before joining TeliaSonera, Mr. J?nsson led an international career in communications working for Nokia, which he joined in 1999. During his 11 years with Nokia, he held various positions in Sweden, the United Kingdom, Finland, and the People?s Republic of China. Mr. J?nsson started his career in communications with Intel Corporation in 1996.  He has studied Business Administration at the University of Stockholm.  Mr J?nsson will join Autoliv in January next year and work together with Mr. ?dman during a transition period.  ?I want to welcome Thomas J?nsson to Autoliv. His broad, international experience in communications will be a great asset for Autoliv?, said Jan Carlson, President & CEO of Autoliv and continued:  ?I would also like to thank Mats ?dman who will retire after 18 years of distinguished service to our company. Mats came to Autoliv shortly after the company went public and has built our communications organization. For this and many other services he has done our company I want to express our sincere thanks?, concluded Jan Carlson  Inquiries:  Jan Carlson, President & CEO, Autoliv Inc. ??????????????? Tel +46-8-587 20 600  Thomas J?nsson, ??????????????????????????????????????????????????????? Tel +46 -70-680 3088 About Autoliv  Autoliv Inc., the worldwide leader in automotive safety systems, develops and manufactures automotive safety systems for all major automotive manufacturers in the world. Together with its joint ventures, Autoliv has approximately 80 facilities with more than 50,000 employees in 29 countries. In addition, the Company has ten technical centers in nine countries around the world, with 21 test tracks, more than any other automotive safety supplier. Sales in 2011 grew by 15% to US $8.2 billion. The Company's shares are listed on the New York Stock Exchange (NYSE: ALV) and its Swedish Depository Receipts on the OMX Nordic Exchange in Stockholm (ALIV sdb). For more information about Autoliv, please visit our company website at www.autoliv.com.

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Source: http://globenewswire.com/news-release/2012/11/28/507837/0/en/Autoliv-Appoints-New-Head-of-Corporate-Communications.html

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Grace that redeems the moments of our lives

A Christian Science perspective.

By Curt Wahlberg / November 28, 2012

I faintly recall the time in second grade when our teacher put the class in pairs to share lockers for the year. The reason this is notable is that I mistakenly got the impression that I was being paired up with a girl. I didn?t like that idea at that age, and I began to cry. All was quickly better though, when the teacher straightened me out.

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It?s possible that I would have forgotten this incident, except for something that happened many years later at the wedding of another classmate. That long-ago locker partner was there, and much to my surprise, he talked angrily about how in second grade I had thought he was a girl. He spoke as if the experience had marred his schoolboy days and perhaps even still affected him.

I felt bad for the guy. And while I don?t really blame my boyhood self, the fact that he still held those feelings made an impression on me. We?ve all heard people?s stories, or have some of our own, of misunderstandings or of cutting comments that have lasting negative effects. ?You can?t sing, just move your lips,? or ?You?re not athletic,? can ring in a person?s ears years later. Today, I feel a responsibility to help us all find the something that will prevent these incidents ? or disarm them and save everybody from the torment.

It?s the grace of God that saves us. People speak of the eternal salvation that God reveals to us, usually in the context of life after death. But God?s saving grace is a presence in human consciousness and can be felt moment by moment right now. It can be ushered into any situation and held onto, helping redeem each moment of our lives.

For me, as the Bible says, the redeeming process involves an ongoing prayer. The second letter to the Thessalonians includes this prayer: ?That the name of our Lord Jesus Christ may be glorified in you, and ye in him, according to the grace of our God and the Lord Jesus Christ? (II Thessalonians 1:12).

The truth of our lives is that we each have a purpose to bring out to help light up the universe and reveal the goodness and value of each one of us. This is our God-given spiritual identity, which is secure and can never be marred. Finding our lives defined by this identity brings a power ? the grace that keeps life going in the right direction. Monitor founder Mary Baker Eddy wrote, ?Throughout all generations both before and after the Christian era, the Christ, as the spiritual idea, ? the reflection of God, ? has come with some measure of power and grace to all prepared to receive Christ, Truth? (?Science and Health with Key to the Scriptures,? p. 333).

For years after that conversation at the wedding, I would occasionally recall the situation and feel bad. But things have evolved for me. The story now is more one of how my life is devoted to ushering in the grace that shows our lives defined by something eternal, special, and good. It?s not defined by something on the surface that?s played out by misunderstandings and awkward situations.

I hope that my prayer has in some way touched my long-ago locker partner. I?ve certainly seen it touch those around me now. I at least do a better job than I would have before in helping my own grade-school kids feel God?s grace, to let that ultimately be what defines their interaction with others. And I feel that, in general, I?m much more skilled at defusing and even preventing awkward situations.

Where is the divine good, God, who redeems our moments? He is right here for us to express with our thoughts, words, and actions. It?s the spiritual ideal of our lives, the Christ, here for us to glorify in our day-to-day interactions and here to leave the final story of who we are and what we?re about.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/NSkJm_34SA0/Grace-that-redeems-the-moments-of-our-lives

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Hoffmann on softball, no politics involved | Hawaii 24/7

Pete Hoffmann | Special to Hawaii 24/7

Normally I write about some politically related issue that is capturing the local headlines. Permit me to change gears a little and relate a sports story.

On Nov. 15, the Hawaiian Pride Senior Softball Team won the 2012 Winter World Championships in the 70+ age group, Major League Division in Phoenix, Ariz.

Of the 18 members of the team that competed in Arizona, 14 are Big lsland residents, to include coach/player Danny Ayala, Mel Hirayama, Frank Amaral, Dave Belaski, Jack McMenimen, Mike Fontes, Herb Leite, Billy Lyman, Clyde Nishioka, Jerry Tulang, George Kodani, Travis Warner, Richard Rodero and Pete Hoffmann.

The tournament victory emphasizes several notable achievements. First, I think it attests to the success of the county?s efforts in promoting senior softball.

When I arrived on the Big Island in 1997, there were eight senior softball teams. There are currently 23 or 24 depending upon the eventual 2013 Kupuna League set up. Senior softball remains one of the county?s biggest success stories for the Department of Parks and Recreation.

Second, when the Hawaiian Pride team travels to the mainland, it regularly faces teams that represent much larger constituencies: New Mexico, Oregon, Central California, for example. We do not enjoy the relatively large pool of potential players from which others draw players.

Nevertheless, we remain very competitive in all aspects of the game, and not just in the 70+ age group.

Which leads to the third conclusion, the quality of play on the Big Island is quite good and the spirit intense. In the Phoenix tournament, four of the six games were decided in the final inning.

Exciting games are the ingredients that bring players back season after season. Big Island Senior Softball certainly confirms the validity of that observation.

Just thought you?d like to be aware that politics is not the only subject we can discuss ?

?

You might be interested in:

  1. Softball: Kohala takes eighth
  2. HI-PAL Halloween Havoc basketball tournament open for entries
  3. Softball: All isle teams out of the title run
  4. Poi Pounder Baseball Classic champions announced
  5. UH-Hilo?s Sueda is the PacWest softball player of the week

Source: http://www.hawaii247.com/2012/11/27/hoffmann-on-softball-no-politics-involved/

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The Load She Should Have Swallowed | Step Talk

So last week we are sitting at the resort in Cancun having a lovely dinner. Somehow the Stepshit(15) brings up how he was a "mistake." Dad starts to defend it saying how he was made out of love blah blah blah and then I chimed in he was a load his Mom should have swallowed. Everyone laughed and then fat ass SS made a sad face. But, it stopped the conversation in it's tracks, LOL!

When we got back our hotel room I told my H that I would say that from now on whenever stuff like that comes up. I'm SICK of it! I've been with DH for 9 years. I'm over it! I also told him I'm over their stories of when they were a family. My youngest SS does it on purpose to exclude me from the conversation. It's been 9 fricken years! We have our own memories by now. Besides, how many times can you hear the same stories over and over!?

Source: http://www.steptalk.org/node/94468

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Tuesday, November 27, 2012

Monday Brief: Droid DNA review, RIM's media blitz, a WP8 showdown, and more!


Mobile Nations



Source: http://feedproxy.google.com/~r/androidcentral/~3/-I-b9fBfM24/story01.htm

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Be Patient With Social Media & Networking ? It Takes Time - Talinorfali

In this new generation and in time of social media and networking with this new age in Internet communications technology with information being transmitted in seconds all over the world with so many types of gadgets and electronic devices, I am sure business people, bloggers, advertisers, designers, web designers, those seeking employment, social marketing, promoters feel the pressure of so much competition going on around them with networking and all the time spent with promotions, making a living with billions of people on the world wide web, and As I am sure my fellow bloggers and I feel the pressure all the time. It is an interesting time we live in these days with everything simplified for us and how incredible time has changed with the new age in technology. Now although most companies want you to send an electronic mail resume and cover letter to the employer and sometimes you wonder are they deleting it or are they really reading the resume and cover letter? There maybe 200 applicants for that position. Nowadays it?s become so hard to seek employment because so many people are seeking the same things. Its become such a stressful time, but I believe that patience and getting the right networking and knowing the right people will get you there. Unfortunately it is like that now. It is not a matter of what you know anymore, it is who you know in that company or a referral.

It is just like the way it takes time to build your online profile, sometimes it takes less. It depends on how you promote yourself and how you portray yourself. It takes a lot of patience, determination, dedication to get on up there. The internet has many people, and if social networking, marketing, promotions, writing, blogging, and being a guest blogger for any company or anyone, and if it is your calling, do it, and charge people with a decent amount and do research on how much you should charge for your services, and if you are good at what you do, and how you do it, they will hire you, no problem. Hey, were all great at doing something in the world, and it is important to get yourself out there and not be afraid of taking chances and doing the best of your ability, Creating an online profile for yourself is great, a portfolio is great so that you can share your accomplishments, and when people give you blogging awards, inspirational awards, and if you are on so many peoples blog sites with ping backs, link backs, these are all a plus and when you include all this in your page, you will be praised and you will go to great lengths.

In recent weeks, I have been more interactive with my fans, and those who come to my blog and I try to reply to as many comments as I am able to. I love visiting other peoples blogs, and give them a boost. I know some people struggle to get people to come to their blogs to read what is happening in their world and what they are up to and among writing for a living and making something out of themselves. It takes a long time and I do feel what they are feeling. I started blogging in another blog provider on Google, and I was not getting anywhere and in one year I had about 5000 people only visiting my site and I felt like I was getting no where. My friend suggested WordPress and I said, let me make an account there and in no time at all, the stats kept increasing and when I began to write more and make more content, things just took off from there. I know some of my blogs require improvement on my writing style, and little bit of the grammar, but I am learning and It is never too late to learn. Social Networking is such a great tool and it will take time and effort, but working at it hard will get you to places, you wouldn?t even imagine.

Maintaining your blog, and maintaining your social networking profiles with new content, and also when you create a twitter account and know how to tweet, you will see a big difference and you will see many people and companies starting to follow you. When you are on Facebook, be mindful to know what your posting and how you are posting it. It is good to keep your standards and everything about you high. Keep your head up high, and do not write so many negative status messages and negative quotes as people pick up on it and they wouldn?t want to engage and be interested with someone who is always bringing themselves down. Bring yourself up, and always write about positivity, determination and things you are good at, and qualities that you have. It is important to put yourself out there with the right attitude, enthusiasm and mean what you say when you write positivity and when you say nice things and be kind to others, and make yourself and your reputation high, the sky is the limit and you will have so many offers and so many opportunities knocking, but it all starts with the way you portray your character and your willingness to try and do your best. You can do it, and will see how you will improve.

How you social network and how you deal with situations online will always be something people will remember and don?t be afraid to put your name out there, because your social networking profile will be like your business card and its important to put a nice and professional photo of yourself or a nice photo of you everywhere and keep that trend going. There are many websites such as facebook, twitter, pinterest, YouTube, linkedin, myspace, and more websites that will make it easy for you, but it is all up to you and in your hands on how you deal with the way you handle yourself online. When your a blogger and when your a dedicated blogger, and want to excel and do your best, engage with other authors and those who have published books in the past and contact them and ask them how its done and what is involved. The internet is the biggest research hub of the world. You can find all the tips and tricks and contact information to people. You will be amazed.

Try it out for yourself and see where you will go with life.? Enjoy the whole process and do not be afraid. All the best in your journey!

Source: http://talinorfali.wordpress.com/2012/11/27/be-patient-with-social-media-networking-it-takes-time-dedication/

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Monday, November 26, 2012

Home Sales in Cash | Real Estate Agents Delight - Ginny's RI House ...

Home Sales in Cash | Real Estate Agents Delight

Home Sales in Cash | Real Estate Agents Delight?. ?RI Cash Home Buyers Wanted! ?In?real estate?home sales right now the difference between a successful home closing and not closing can be the

Cash RI Home Buyers Wanted in RI real estate

Cash Buyers Wanted

mortgage financing. ?Home buyers seem to forget that every little thing on their?credit?can be the make or break item in getting a mortgage or not. ?This is not saying that it is a mortgage lenders issue. ?Many times it is the buyer who has made a misstep somewhere along their life journey to not be quite lendable to yet. ?

Well cash rich home buyers are out for?waterfront RI real estate?right now. ?In fact, the market reports for southern RI real estate home sales in 2012 show that a high percentage of homes are being purchased with cash. ?Cash from retirement accounts, investments, stock market liquidations and sometimes grandma's hidden stash of cash.

It just smoothly sails through to closing. ?Where are the bumps to be anticipated? ?Well mostly in the home inspection process where the cash home buyer may ask for more of the home repairs be completed by the sellers as part of the final sales price. ?A home sales in cash is a real estate agents delight!

My experience has shown that some buyers will start the mortgage financing process and just stop the it in the middle of the process! ?Throw their hands up if they have the cash and purchase a home outright. ?It is the easiest way of home purchase.?

Buyers who do have enough equity in their home can down size their home into a smaller home or condo to fit their needs easier. ?Again when you have the cash it is a smoother home purchase.

The point is you need to figure what works best for you and your family at this time in your lives.

This is the time to talk with a knowledgeable?RI real estate agent?that can make the process go smoother. ?Have time to chat about your current home or the one you have been thinking about? ?I would love the opportunity to help you so call me at?401.529.7849?or email me at?RiByTheBay@gmail.com?today. ?Home Sales in Cash | Real Estate Agents Delight.

~~~~~~~~~~~~~~~~~~~~~~~~~~~

Ginny Lacey Gorman?is a?waterfront Rhode Island Real Estate Agent?who works and knows the?Southern RI?geographic area of homes for sale, schools, happenings and important tidbits of information?well.

Coastal, water view, ocean front, luxury?and?waterfront Rhode Island real estate?are my specialty.??If your considering?Buying, Selling or Relocating to Rhode Island and need a real estate Professional it would be my pleasure to help you!????When you are in need of an internet savvy RI realtor??who sells homes in this real estate market,?call Ginny today at?401.529.7849.

This blog ? and its contents is original to Ginny Lacey Gorman

Ginny L. Gorman a purveyor of Fine RI Real Estate??

Specializing in waterfront, ocean front, vacation, coastal and luxury homes for sale in North Kingstown, South Kingstown, Narragansett, Jamestown, Charlestown, East Greenwich, Exeter, West Greenwich, Westerly RI and beyond ...? I sell dreams! ?because there is no place like home...the RI Realtor in the Sparkly Red Shoes.

Looking for a terrific Rhode Island Realtor?? Let me GOOGLE one for you!

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Facebook ? Flckr? LinkedIn RSS Feed to My Blog

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cell: 401.529.7849?? office: 401.884.4100 ext.268 ? Ginny Lacey Gorman, Realtor

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Source: http://ginnysrihousehuntblog.com/post/3530939/home-sales-in-cash-real-estate-agents-delight

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Athletic arms race pushes children's sports to extremes ...

By

November 25, 2012

Shawn Worthy admits he's a competitive guy ? and a competitive parent, sometimes.

Yet even he was floored when a couple of moms he met at a pro junior golf tournament told him that their teen daughters were entered in 30 such events this past summer.

"Why are these young ladies out on the golf course playing competitively four or five days a week?" Worthy asked himself.

His own 16-year-old daughter, Soleil, holds down a job while participating in a few tournaments each summer. She and the other young women are good, Worthy says, maybe talented enough to play in college.

But 30 tournaments?

"If you're a future Olympian, I get it. But for these kids who will never reach that level, that's what I don't get," says Worthy, a professor at Metropolitan State University of Denver with an interest in sports psychology.

"What does it say about our culture that we go to this extreme?" he asks. "And that we push our kids to this extreme?"


Race to succeed

It's not just golf. Many parents, coaches and researchers see a steady upping of the ante in youth sports, with kids whose families can afford the time and cost involved playing more, practicing more and specializing in one sport at younger ages.

Parents are driven by a desire to help their children stand out and the fear that, if they don't, their kids will be left behind. To keep pace, they're often traveling hundreds if not thousands of miles a year for games and tournaments. Some parents send their children to personal trainers, or to the growing number of so-called elite training facilities that have opened in recent years.

Often, the goal is to simply land a spot on the local high school team, an accomplishment once taken for granted. Or a young person may try to get on the roster in the growing private club team system ? an even more exclusive route that some top teenage athletes are choosing, especially when high schools cut coaches and opportunities.

"It's an athletic arms race," says Scott VanderStoep, a psychology professor at Hope College in Holland, Mich., who studies youth sports.

And it starts early.

"It sort of spreads throughout the community, and then it reduces down in age," VanderStoep says. "If it's OK for 14-year-olds, then it's OK for a 12-year-old, or a 10-year-old."

VanderStoep admits that, as a dad of two daughters who play volleyball, even he feels beholden to the system. For his daughters, that has meant weight-lifting camps and tournaments, and seemingly endless required practices and packed schedules.

"You feel obligated to do it. You want to give your kids the opportunity," he says. "And if they don't show up, they lose opportunities to play."


Making sacrifices

Corinne Henson, a mom in suburban Chicago, knows about those hard choices. Her sons, 11-year-old Tyler and 14-year-old Dylan, play year-round baseball on different traveling teams and also manage to squeeze in basketball and football for their local park district.

But there are sacrifices, especially for their parents. Time spent on sports has meant giving up their longtime campsite in Indiana, where they'd kept a travel trailer. They simply have no time to go there.

"Our vacations are baseball trips," Henson says. She figures they spend several thousand dollars a year on travel, team fees and equipment. Often, one parent is taking Dylan to one game or practice, while the other parent carts Tyler to the other.

When they were younger, their boys regularly missed birthday parties and other events because of games. But the most difficult decision came earlier this year, when Dylan's best friend was struck and injured by a hit-and-run driver.

Their town, Oak Forest, Ill., had a fundraiser for the friend in July. But Dylan, a catcher who is captain of his traveling baseball team, had four tournament games that day. He decided he had to be at the tournament, and showed up at the fundraiser as it was wrapping up.

His friend understood. "I would have done the same thing," he told Dylan.


$5,000 to $6,000 a year

Diane Hughes, a mom in New Jersey, also knows that many outsiders would look at her 10-year-old son's travel-team baseball schedule and shake their heads.

"It really sounds crazy, I know," Hughes says.

It often means he has multiple three-hour practices each week, a 45-minute drive from their home. Weekend tournaments usually consist of four or five games. And Hughes figures she spends $5,000 to $6,000 a year so he can participate ? an amount that is pretty standard and often more, especially for those who seek out elite training.

There are many positives, Hughes says.

"In the long run, I want him to have his time structured, so I love the fact that he loves it so much. It's exercise. It's building a skill. It's fun ? and it's fun to watch them," Hughes says.

Her biggest concern? That, by the time he gets to high school, he'll be tired of baseball.


Focus on academics

In the Henson house, the rule is simple: "Homework first," says mom, who's a teacher.

Jon Butler, executive director of Pop Warner Little Scholars, an international youth football and cheerleading program, says that's a perspective he hears less and less.

"The first several years I was here, our biggest concern was training coaches ? the overzealous Vince Lombardi coach," says Butler, who's been in his position for more than 20 years. "That started to change in the late 1990s, when we started to be concerned with the overzealous parent."

In more recent years, he's watched as parents have clamored to find ways to improve their children's athletic prowess. He says his advice to them ? "don't hire a speed coach, hire a tutor" ? is often met with disgust.

"They respond like I've lost a few marbles along the way," he says. "It's not what they want to hear."

Bill Jaworski, a dad who's also a youth baseball coach in New Jersey, says he is often "shocked and chagrined" at how easily some parents lose perspective about their kids' sports.

"These are people you see at the pub, or on the train, or out on the street. They're just normal folks ? and then you get them to the game, and they turn into these rabid freakazoids," says Jaworski, who's also a philosophy professor at Fordham University.

It's just different than when he was a kid, Jaworksi says. He played baseball at the local park with friends or in the backyard. Today, he's seeing kids as young as age 7 learning the skills at elite training facilities, some that focus on specific sports and others on overall fitness.


"A better person'

Billy Hirschfield, now 16, was 11 when his dad first took him to an establishment called NX+Level, in Waukesha, Wis., a suburb of Milwaukee.

Now a 6-foot-6, 270-pound defensive tackle and end, he's so big and muscular ? and so dedicated to his training ? that his friends call him "the freak."

"I never in a million years thought it would be like that," says his dad, who figures he spends $8,000 to $10,000 a year on sports, including training and travel to tournaments.

It's all been worth it, he says.

"Why wouldn't you spend that on your son to make him a better person?" his dad asks. "And if he ends up walking away with a scholarship, it was the best investment I could have ever made."

Sports can be seen as a ticket to something bigger, a way to set a kid apart from the pack.

"You try and build the perfect kid," says Adam Naylor, a clinical assistant professor of sports psychology at Boston University who works with parents and athletes, some as young as age 12.

"It leads to overtraining, overuse and an over-committed kid, which has fallout. But it's really tough to see that in the moment."


Living through children

Naylor recalls one mom who told him: "In this town, if you don't play club soccer, you're told your kid won't make it in life. But we only have money to play town soccer."

She felt guilty that she couldn't afford the more expensive private league. She felt pressured, as many parents do.

Other times, it's the parents doing the pushing ? as Worthy sees it, their quest to boost their own self-esteem with their children's accomplishments. He calls it "vicarious glory." He recalls how those moms on the golf course followed their daughters on every golf round and introduced themselves not by their own names but as "so and so's mom."

Still, even he concedes that his competitive parent has shone through occasionally.

He remembers telling a buddy a few years back that his daughter was getting into golf after giving up competitive gymnastics because of injury.

"If she's going to play," the friend advised, "buy her the best gear possible because everybody out there is going to have it."

Did Worthy do it?

"Yep," he says. "Because if you don't, then it's not even fair."

As psychologist Wendy Grolnick sees it, that's just parents doing what they're wired to do ? responding to a very primal instinct to protect their children and ensure their survival.

"It's not out of a sense of living through your child or narcissism. Parents love their kids, and they don't want them to miss out," says Grolnick, a professor at Clark University who wrote the book "Pressured Parents, Stressed-out Children: Dealing with Competition While Raising a Successful Child."

The key is to keep it in check.

"There's just so much competition in the air," she says. "Very nice people are feeling this way."


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Source: http://www.poconorecord.com/apps/pbcs.dll/article?AID=/20121125/NEWS90/211250343/-1/rss01

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Sunday, November 25, 2012

Pope tells new cardinals: shun "worldly logic of power"

VATICAN CITY (Reuters) - Pope Benedict on Sunday told six prelates newly elevated to the rank of cardinal that all Catholic leaders should shun the "worldly logic of power" and stick to spreading the gospel.

The pope presided at a solemn mass in St Peter's Basilica with the six men from the United States, India, Nigeria, the Philippines, Lebanon and Colombia the day after they became cardinals at a ceremony known as a consistory.

"To be disciples of Jesus, then, means not letting ourselves be allured by the worldly logic of power, but bringing into the world the light of truth and God's love," he said.

"To you, dear and venerable brother cardinals - I think in particular of those created yesterday - is entrusted this demanding responsibility: to bear witness to the kingdom of God, to the truth."

The new cardinals are American Archbishop James Michael Harvey, Baselios Cleemis Thottunkal, a major archbishop of the Syro-Malankara rite in India, Archbishop Ruben Salazar Gomez of Bogota, Archbishop Luis Antonio Tagle of Manila, Beatitude Bechara Boutros Rai, patriarch of the Maronite Catholic Church in Lebanon, and Archbishop John Olorunfemi Onaiyekan of Abuja.

Indian women at the mass wore saris and African women wore traditional dresses. Prayers were read in Arabic, Hindi, Yoruba and Tagalog as well as English, French and Italian.

"I think it's about time that we have a diverse and more colorful bunch of cardinals," said Leslie Ryan, a pilgrim who attended the consistory.

"If you want to bring all the Catholics together you need to have a diverse group of cardinals and it's about time."

The choice of the cardinals, ranging in age from 53 to 72, looked like an attempt to counter criticism that he has in the past neglected the needs of the developing world.

CARDINAL ELECTORS

All six are "cardinal electors", under 80 years old and therefore eligible to enter a conclave that will one day choose Benedict's successor.

Two of the new cardinals, Boutros Rai, 72, of Lebanon, and Onaiyekan, 68, of Nigeria, are from countries with significant Muslim populations.

In Nigeria, which is about 50 percent Muslim, the Islamist sect Boko Haram has killed hundreds of people in attacks since 2009. Many of the attacks have been on Christians and churches.

"The Boko Haram, the young men who are throwing bombs all over the place in Nigeria, have been rejected by the mainstream of Islam in Nigeria. But somehow, the way the Islamic religion is organized there's nobody who can tell them 'Stop it!'," Onaiyekan told Reuters in an interview.

"So the rest of us are actually, you can say, suffering because of the inner difficulties within Islam. But that's the reality we have to live with and we are doing our best. What is important for people to know is that it is not a case of Nigerian Muslims at war with Nigerian Christians."

Tagle, 55, of Manila, heads the largest Catholic church in Asia, where Christians are minorities in most countries.

"I think we have been used to a humble and hidden type of existence and it doesn't lead us to pessimism," he told Reuters.

"Being a small minority doesn't mean the church is dead," he said. "Of course, who doesn't want the numbers to increase? But there are things in life that are not measured only by numbers."

(Reporting by Philip Pullella; editing by Andrew Roche)

Source: http://news.yahoo.com/pope-tells-cardinals-shun-worldly-logic-power-115258963.html

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East Pennsboro Township Historical Society keeps history current ...

?Few cars pass by the small building tucked away on a tidy corner at 410 Cherry St. in East Pennsboro Township, and it?s possible that even fewer residents are aware that the structure even exists.

Certainly the foot traffic has diminished since the days when it was known to residents as the West Fairview Borough Building, but a faithful group of volunteers make a regular pilgrimage to the site now known as the East Pennsboro Historical Society.

It?s their way of keeping history alive.

Founded in 1999 by East Pennsboro Twp. resident Herb Kruger, the all-volunteer, historical organization houses artifacts and relics of a bygone era. Kruger passed away in 2007, but his work lives on in the nonprofit.

Executive Director Jim Leonard runs the show, and you could say it?s in his blood as he launches into a history of the Enola yards and the subsequent founding of the township.

?In 1903, the Rockville Bridge was completed and there was so much traffic that the yards in Marysville and Harrisburg couldn?t handle all the coal business. The Pennsylvania Railroad, realizing this, surveyed the area and founded Enola Realty Company to build a town to house the workers,? said Leonard, who retired from the railroad and whose father and grandfather also worked on the rails. ?From World War II through the 1950s, Enola had the largest classification yard in the world,? he said.

This spring, the Historical Society was given a facelift of sorts to better show off its extensive collection of railroad artifacts, which are housed with other relics of the era in well-lit, glass display cases. The collection of artifacts is often rotated, so you?re likely to see different items every few months, often based on a theme. The current theme in the small museum is music and a cape from a Midway Drum and Bugle Corps member, along with a 1934 picture of the Midway Drum Corps. They are on display alongside majorette hats and other music-related items from the 1930s.

Leonard?s goal is to increase the visibility of the organization, which currently has about 500 members.

?We?d like more people to get involved in educating our children about the history of the community,? he said. ?Teachers can bring kids here on a small group tour bus to learn about their heritage.?

?Our problem right now is that the younger people don?t seem to be interested, and we?d like to see more of them get involved,? historical society president Tom Crognale said.

Every year, the society gives a $1,000 Herb Kruger memorial scholarship, which is open to any member of the historical society or their child, grandchild, nephew, niece, brother or sister who will be attending college.

?In this day and age, we?re surprised we haven?t seen more interest in it,? Leonard said.

In addition to seeking increased visibility and membership, the society also needs volunteers and always welcomes artifact donations. ?We take anything that might be of value historically,? Crognale said. ?Pictures with names on them are ideal.?

Looking to the future, the society that celebrates the past is currently working on the 200th anniversary celebration of the founding of West Fairview.

?We?ll have parades and festivals featuring past and current history and we are now accepting donations for the celebration, which will take place in 2015,? Crognale said. ?We hope to get the entire community involved.?

For those interested in joining the East Pennsboro Twp. Historical Society, the cost is $10 for an individual membership and $20 for a family membership, which includes an invitation to the biannual dinners and two seasonal newsletters.

Source: http://www.pennlive.com/midstate/index.ssf/2012/11/east_pennsboro_township_histor.html

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Saturday, November 24, 2012

Clashes in Cairo after Mursi seizes new powers

CAIRO (Reuters) - Angry youths hurled rocks at security forces and burned a police truck as thousands gathered in central Cairo to protest at Egyptian President Mohamed Mursi's decision to grab sweeping new powers.

Police fired tear gas near Tahrir Square, heart of the 2011 uprising that toppled Hosni Mubarak at the height of the Arab Spring. Thousands demanded that Mursi should quit and accused him of launching a "coup".

There were also violent protests in Alexandria, Port Said and Suez.

Mursi on Thursday issued a decree that puts his decisions beyond any legal challenge until a new parliament is elected. Opponents immediately accused him of turning into a new Mubarak and hijacking the Egyptian revolution.

"This is the point of no return for Mursi. He has dug himself deeper in a hole and won't know how to get out of it," said Ahmed Saleh, an activist who said many would stay in Tahrir square until Mursi withdrew the decree.

"The people want to bring down the regime," shouted protesters in Tahrir, echoing a chant used in the uprising that forced Mubarak to step down.

The United States, the European Union and the United Nations expressed concern at Mursi's move.

Mursi's rivals condemned him as an autocratic pharaoh who wanted to impose his Islamist vision on Egypt.

The president's aides said the decree was intended to speed up a protracted transition to democracy that has been hindered by legal obstacles

"I am for all Egyptians," Mursi said on a stage outside the presidential palace, adding that he was working for social and economic stability and remained committed to the revolution.

JUDGES MEET

Egyptian judges will meet on Saturday to respond to Mursi's move, which put him above the judicial oversight. The judges could threaten to go on strike, which would bring the judiciary to a halt.

Some non-Islamist political parties called for a million-strong march on Tuesday to demand that Mursi rescinds his decree.

But Islamist parties, including the Building and Development Party, accused Mursi's opponents of undermining the democratic process that brought him to office.

"Those calling for the downfall of President Mohamed Mursi have rejected democracy because President Mursi has been democratically elected by popular will," the party said in a statement. Mursi's decree would "save the revolution from the remnants of Mubarak's regime", it said.

Buoyed by accolades from around the world for mediating a truce between Hamas and Israel in the Gaza Strip, Mursi on Thursday ordered that an Islamist-dominated assembly writing the new constitution could not be dissolved by legal challenges.

Mursi, an Islamist whose roots are in the Muslim Brotherhood, also gave himself wide powers that allowed him to sack the unpopular public prosecutor and opened the door for a retrial for Mubarak and his aides.

TURBULENCE AND TURMOIL

The president's decree has consolidated his power but looks set to polarize Egypt further, threatening more turmoil in a nation at the heart of the Arab Spring.

In Alexandria, north of Cairo, protesters ransacked an office of the Brotherhood's political party, burning books and chairs in the street. Supporters of Mursi and opponents clashed elsewhere in the city, leaving 12 injured.

A party building was attacked by stone-throwing protesters in Port Said, and demonstrators in Suez threw petrol bombs that burned banners outside the party building.

Although Washington has praised Egypt for its part in bringing Israelis and Palestinians to a ceasefire on Wednesday, it expressed reservations about Mursi's latest move.

"The decisions and declarations announced on November 22 raise concerns for many Egyptians and for the international community," State Department spokeswoman Victoria Nuland said in a statement.

The European Union urged Mursi to respect the democratic process, while the United Nations expressed fears about human rights.

"The decree is basically a coup on state institutions and the rule of law that is likely to undermine the revolution and the transition to democracy," said Mervat Ahmed, an independent activist in Tahrir protesting against the decree.

Leading liberal Mohamed ElBaradei, who joined other politicians on Thursday night to demand the decree was withdrawn, wrote on his Twitter account that Mursi had "usurped all state powers and appointed himself Egypt's new pharaoh".

Almost two years after Mubarak was toppled and about five months since Mursi took office, Egypt has no permanent constitution, which must be in place before new parliamentary elections are held.

An assembly drawing up the constitution has yet to complete its work. Many liberals, Christians and others have walked out accusing the Islamists who dominate it of ignoring their voices over the extent that Islam should be enshrined in the new state.

(Additional reporting by Tom Miles in Geneva and Sebastian Moffett in Brussels; Editing by Giles Elgood)

Source: http://news.yahoo.com/clashes-cairo-mursi-seizes-powers-053441160.html

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VCs Still Chasing Web Companies, But With Less Cash - Russ ...

Venture investors still have a healthy appetite for early-stage consumer Internet companies, but those startups are having a harder time raising follow-on financing.

Overall the amount invested in consumer information services was off 42% in the first nine months as the difficulties of newly public Internet companies such as Facebook and Zynga cast doubt on the business models and valuations of social media companies.

Read the rest of this post on the original site

Source: http://allthingsd.com/20121124/vcs-still-chasing-web-companies-but-with-less-cash/

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How Do Porcupines Mate? Very Carefully.

Careful porcupines. Porcupines must take care before coitus

Photo by John Pitcher/iStockphoto/Thinkstock.

These days, it?s difficult to roll out of bed without being hit in the face with a four-headed echidna penis. We are living in the Golden Age of Internet Animalia. Hardly an hour passes without the discovery of some ridiculous-looking new species, bizarre adaptation, or horrendous sex organ. We?re so accustomed to this by now that we just go, ?Nature?s crazy, man!? and get on with our Facebooking?er, jobs.

And that?s great! People are excited about animals and science and bizarre penises?well, penises are an easy sell?but it?s also sort of weird that we may know more about yeti crabs, honey badgers, and blue dragon sea slugs than we do about some of the beasties in our own backyards.

In forests across Canada and the United States, a peculiar mating ritual takes place each fall. If your windows aren?t painted shut, you might open them at night and listen for the tender sounds of porcupine coitus?stark, night-piercing shrieks that could be likened to the noises produced by a banshee banging a Velociraptor.

I know what you?re thinking?quills. It?s true, the North American porcupine (Erethizon dorsatum) is equipped with something like 30,000 needle-sharp back daggers, and many of them stand between the female?s hoo-ha and the next generation of prickly progeny. But the screaming actually comes long before the love-making.

You see, the biggest holdup to porcupine reproduction is location. Except for mamas raising babies?which are known adorably as porcupettes?porcupines are mostly solitary creatures. And when the female is ready to mate, she has just an 8- to 12-hour window of fertility to work with.

This means the fellas need to come from distant territories to find, win, woo, and mount her if they are to pass on their genes. Females assist in this process before they come into estrus by lacing the air with a pungent perfume?a come-hither scent created by a combination of vaginal mucous and urine that not even Brad Pitt could make appealing.

Either way, the musk-shake brings all the boys to the yard, and once they are there, it?s a brawl for dominance. Uldis Roze knows these battles by their aftermath: ?a storm of loose quills.? Roze has 35 years of experience working with these creatures and is widely regarded as the Porcupine King. (He also has a delightful new book available?guess what it?s about!) After listening to porcupines battle one fall night, Roze returned the next day and collected 1,474 quills belonging to three separate males. Some of the quills bore signs of bite marks, showing that porcupines are practiced in removing rivals? quills from their own skin after such skirmishes.

Once a male has won access to his ladyfriend, the right to mate is his to lose. At this point, many male animals would simply mount the female whether she was interested or not. In humans, we call this rape. Using the same term with animals is problematic, but walk with me.

If rape is nonconsensual sex, then ducks rape. Seals rape. Male bedbugs stab the females with their penis and then leave it there. Water striders coerce sex by threatening to call in predators if the females don?t submit. Even dolphins, animals of respected intelligence and the default subject of chick tattoos, gang rape.

None of this is to minimize the crime of rape in humans. I bring it up only to note that the animal kingdom can be a dark place. When dominant male elephants are poached or culled out of the social hierarchy, adolescent males develop strange, violent behaviors, like wantonly murdering rhinoceroses. But not without raping them first. And while I don?t claim to know what goes on in a rhinoceros? brain, I think you could probably define sentience as having a major problem with all of that.

But porcupines? My friends, porcupines are rape-proof. And not rape-proof like the magical vaginas of Todd Akin?s fever dreams. I mean rape-proof like the anti-rape condom.

A porcupine?s main defense against predators consists of keeping its backside to a predator. Get too close and you?ll snag 500 quills engineered to embed themselves deeper and deeper into flesh. A mouth full of these painful pins has caused many an animal to starve to death. In fact, the porcupine is so well-respected, it wanders the forest day or night without much hurry or fear. Few animals are clever enough to successfully hunt porcupines, though mountain lions, fishers, and Chevy Impalas have the most success. That mess of quills is equally effective against its own kind.

Thus instead of force, the male porcupine must use persuasion. He first climbs the female?s tree and stands watch from a lower branch until the time is right.

(Yes, porcupines climb mother-cussing trees! Unfortunately, being the second-largest rodent in North America, porcupines also fall out of trees quite a bit. At least their quills are coated with antibacterial fatty acids that seem to protect against infection after self-impalement.)

Source: http://feeds.slate.com/click.phdo?i=b821cd7441af1b2fb416d737a1e134ad

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Friday, November 23, 2012

ScienceDaily: Gene News

ScienceDaily: Gene Newshttp://www.sciencedaily.com/news/health_medicine/genes/ Genes and Genetics News. Read today's medical research in genetics including what can damage genes, what can protect them, and more.en-usFri, 23 Nov 2012 21:42:39 ESTFri, 23 Nov 2012 21:42:39 EST60ScienceDaily: Gene Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/health_medicine/genes/ For more science articles, visit ScienceDaily.New insights into virus proteome: Unknown proteins of the herpesvirus discoveredhttp://www.sciencedaily.com/releases/2012/11/121123092132.htm The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system scientists have shown that the genome of this virus contains much more information than previously assumed. The researchers identified several hundred novel proteins, many of which were surprisingly small.Fri, 23 Nov 2012 09:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121123092132.htmScientists describe elusive replication machinery of flu viruseshttp://www.sciencedaily.com/releases/2012/11/121122152928.htm Scientists have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to ?see? one of influenza?s essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus?s vulnerabilities that are sure to be of interest to drug developers.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152928.htmProtein folding: Look back on scientific advances made as result of 50-year old puzzlehttp://www.sciencedaily.com/releases/2012/11/121122152910.htm Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152910.htmStep forward in regenerating and repairing damaged nerve cellshttp://www.sciencedaily.com/releases/2012/11/121121145638.htm Researchers recently uncovered a nerve cell's internal clock, used during embryonic development. This breakthrough could lead to the development of new tools to repair and regenerate nerve cells following injuries to the central nervous system.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145638.htmArchitecture of rod sensory cilium disrupted by mutationhttp://www.sciencedaily.com/releases/2012/11/121121145621.htm Using a new technique called cryo-electron tomography, scientists have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145621.htmAging: Scientists further unravel telomere biologyhttp://www.sciencedaily.com/releases/2012/11/121121130933.htm Researchers have resolved the structure of that allows a telomere-related protein, Cdc13, to form dimers in yeast. Mutations in this region of Cdc13 put the kibosh on the ability of telomerase and other proteins to maintain telomeres.Wed, 21 Nov 2012 13:09:09 ESThttp://www.sciencedaily.com/releases/2012/11/121121130933.htmDrug resistance biomarker could improve cancer treatmenthttp://www.sciencedaily.com/releases/2012/11/121121130811.htm Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a new study. The study reveals a biomarker that can predict responses to cancer drugs and offers a strategy to treat drug-resistant tumors based on their genetic signature.Wed, 21 Nov 2012 13:08:08 ESThttp://www.sciencedaily.com/releases/2012/11/121121130811.htmGenome packaging: Key to breast cancer developementhttp://www.sciencedaily.com/releases/2012/11/121121130703.htm Two recent studies delve into the role of chromatin modifying enzymes and transcription factors in tumour cells. In one, it was found that the PARP1 enzyme activated by kinase CDK2 is necessary to induce the genes responsible for the proliferation of breast cancer cells in response to progesterone. In another, extensive work has been undertaken to identify those genes activated by the administration of progesterone in breast cancer, the sequences that can be recognized and how these genes are induced.Wed, 21 Nov 2012 13:07:07 ESThttp://www.sciencedaily.com/releases/2012/11/121121130703.htmShort DNA strands in genome may be key to understanding human cognition and diseaseshttp://www.sciencedaily.com/releases/2012/11/121121130643.htm Previously discarded, human-specific ?junk? DNA represents untapped resource in the study of diseases like Alzheimer?s and autism.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130643.htmBiomarking time: Methylome modifications offer new measure of our 'biological' agehttp://www.sciencedaily.com/releases/2012/11/121121130633.htm In a new study, researchers describe markers and a model that quantify how aging occurs at the level of genes and molecules, providing not just a more precise way to determine how old someone is, but also perhaps anticipate or treat ailments and diseases that come with the passage of time.Wed, 21 Nov 2012 13:06:06 ESThttp://www.sciencedaily.com/releases/2012/11/121121130633.htmKidney tumors have a mind of their ownhttp://www.sciencedaily.com/releases/2012/11/121121104552.htm New research has found there are several different ways that kidney tumors can achieve the same result -- namely, grow.Wed, 21 Nov 2012 10:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121121104552.htmMechanism to repair clumped proteins explainedhttp://www.sciencedaily.com/releases/2012/11/121121104416.htm Clumped proteins can be dissolved with the aid of cellular repair systems -- a process of critical importance for cell survival especially under conditions of stress. Researchers have now decrypted the fundamental mechanism for dissolving protein aggregates that involves specific molecular chaperones.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104416.htmNovel mechanism through which normal stromal cells become cancer-promoting stromal cells identifiedhttp://www.sciencedaily.com/releases/2012/11/121121104401.htm New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to new research.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104401.htmNew test for tuberculosis could improve treatment, prevent deaths in Southern Africahttp://www.sciencedaily.com/releases/2012/11/121120194932.htm A new rapid test for tuberculosis (TB) could substantially and cost-effectively reduce TB deaths and improve treatment in southern Africa -- a region where both HIV and tuberculosis are common.Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194932.htmEvolution of human intellect: Human-specific regulation of neuronal geneshttp://www.sciencedaily.com/releases/2012/11/121120194926.htm A new study has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish us from other primates, including monkeys and apes, and as neurons are at the core of our unique cognitive abilities, these features may ultimately hold the key to our intellectual prowess (and also to our potential vulnerability to a wide range of 'human-specific' diseases from autism to Alzheimer's).Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194926.htmRibosome regulates viral protein synthesis, revealing potential therapeutic targethttp://www.sciencedaily.com/releases/2012/11/121120132906.htm Rather than target RNA viruses directly, aiming at the host cells they invade could hold promise, but any such strategy would have to be harmless to the host. Now, a surprising discovery made in ribosomes may point the way to fighting fatal viral infections such as rabies.Tue, 20 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121120132906.htmHow does antibiotic resistance spread? Scientists find answers in the nosehttp://www.sciencedaily.com/releases/2012/11/121120121835.htm Microbiologists studying bacterial colonization in mice have discovered how the very rapid and efficient spread of antibiotic resistance works in the respiratory pathogen, Streptococcus pneumoniae (also known as the pneumococcus). The team found that resistance stems from the transfer of DNA between bacterial strains in biofilms in the nasopharynx, the area just behind the nose.Tue, 20 Nov 2012 12:18:18 ESThttp://www.sciencedaily.com/releases/2012/11/121120121835.htmScientists identify inhibitor of myelin formation in central nervous systemhttp://www.sciencedaily.com/releases/2012/11/121120100155.htm Scientists have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduction of nerve cell impulses by forming a sheath around their projections, the so-called axons, at specific locations -- acting like the plastic insulation around a power cord.Tue, 20 Nov 2012 10:01:01 ESThttp://www.sciencedaily.com/releases/2012/11/121120100155.htmTelomere lengths predict life expectancy in the wild, research showshttp://www.sciencedaily.com/releases/2012/11/121119213144.htm Researchers have found that biological age and life expectancy can be predicted by measuring an individual's DNA. They studied the length of chromosome caps -- known as telomeres -- in a 320-strong wild population of Seychelles Warblers on a small isolated island.Mon, 19 Nov 2012 21:31:31 ESThttp://www.sciencedaily.com/releases/2012/11/121119213144.htmCancer: Some cells don't know when to stophttp://www.sciencedaily.com/releases/2012/11/121119171403.htm Certain mutated cells keep trying to replicate their DNA -- with disastrous results -- even after medications rob them of the raw materials to do so, according to new research.Mon, 19 Nov 2012 17:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121119171403.htmMultiple sclerosis ?immune exchange? between brain and blood is uncoveredhttp://www.sciencedaily.com/releases/2012/11/121119163301.htm DNA sequences obtained from a handful of patients with multiple sclerosis have revealed the existence of an ?immune exchange? that allows the disease-causing cells to move in and out of the brain.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163301.htm3-D light switch for the brain: Device may help treat Parkinson's, epilepsy; aid understanding of consciousnesshttp://www.sciencedaily.com/releases/2012/11/121119114249.htm A new tool for neuroscientists delivers a thousand pinpricks of light to individual neurons in the brain. The new 3-D "light switch", created by biologists and engineers, could one day be used as a neural prosthesis that could treat conditions such as Parkinson's and epilepsy by using gene therapy to turn individual brain cells on and off with light.Mon, 19 Nov 2012 11:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119114249.htmBlood cancer gene BCL6 identified as a key factor for differentiation of nerve cells of cerebral cortexhttp://www.sciencedaily.com/releases/2012/11/121119093848.htm The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases. Researchers have opened new perspectives on brain development and stem cell neurobiology by discovering a gene called BCL6 as a key factor in the generation of cortical neurons during embryonic brain development.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093848.htmMinority report: Insight into subtle genomic differences among our own cellshttp://www.sciencedaily.com/releases/2012/11/121118141530.htm Scientists have demonstrated that induced pluripotent stem cells -- the embryonic-stem-cell look-alikes whose discovery a few years ago won this year's Nobel Prize in medicine -- are not as genetically unstable as was thought.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141530.htmSkin cells reveal DNA's genetic mosaichttp://www.sciencedaily.com/releases/2012/11/121118141524.htm The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141524.htmLikely basis of birth defect causing premature skull closure in infants identifiedhttp://www.sciencedaily.com/releases/2012/11/121118141432.htm Geneticists, pediatricians, surgeons and epidemiologists have identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis premature closure of the bony plates of the skull.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141432.htmDNA packaging discovery reveals principles by which CRC mutations may cause cancerhttp://www.sciencedaily.com/releases/2012/11/121117184658.htm A new discovery concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases.Sat, 17 Nov 2012 18:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121117184658.htmHepatitis C treatment's side effects can now be studied in the labhttp://www.sciencedaily.com/releases/2012/11/121116161059.htm Adverse side effects of certain hepatitis C medications can now be replicated in the lab, thanks to a research team. The new method aids understanding of recent failures of hepatitis C antiviral drugs in some patients, and could help to identify medications that eliminate adverse effects. The findings may aid the development of safer and more effective treatments for hepatitis C and other pathogens such as SARS and West Nile virus.Fri, 16 Nov 2012 16:10:10 ESThttp://www.sciencedaily.com/releases/2012/11/121116161059.htmReconsidering cancer's bad guyhttp://www.sciencedaily.com/releases/2012/11/121116124644.htm Researchers have found that a protein, known for causing cancer cells to spread around the body, is also one of the molecules that trigger repair processes in the brain.Fri, 16 Nov 2012 12:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121116124644.htmGene distinguishes early birds from night owls and helps predict time of deathhttp://www.sciencedaily.com/releases/2012/11/121116124551.htm New research shows that a gene is responsible for a person's tendency to be an early riser or night owl -- and helps determine the time of day a person is most likely to die.Fri, 16 Nov 2012 12:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121116124551.htmClues to cause of kids' brain tumorshttp://www.sciencedaily.com/releases/2012/11/121116091226.htm Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.Fri, 16 Nov 2012 09:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121116091226.htmArthritis study reveals why gender bias is all in the geneshttp://www.sciencedaily.com/releases/2012/11/121115210541.htm Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.Thu, 15 Nov 2012 21:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121115210541.htmClass of RNA molecules protects germ cells from damagehttp://www.sciencedaily.com/releases/2012/11/121115172255.htm Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals. Biologists have now identified one way the body does exactly that.Thu, 15 Nov 2012 17:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121115172255.htmQuick test speeds search for Alzheimer's drugs: Compound restores motor function and longevity to fruit flieshttp://www.sciencedaily.com/releases/2012/11/121115152655.htm Researchers report that an efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease.Thu, 15 Nov 2012 15:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115152655.htmProtein-making machinery can switch gears with a small structural change process; Implications for immunity and cancer therapyhttp://www.sciencedaily.com/releases/2012/11/121115133414.htm For the past several years, research has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins. In a new study, scientists have shown that this enzyme can actually also work in another fundamental process in humans.Thu, 15 Nov 2012 13:34:34 ESThttp://www.sciencedaily.com/releases/2012/11/121115133414.htmPlant derivative, tanshinones, protects against sepsis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121115133312.htm Researchers have discovered that tanshinones, which come from the plant Danshen and are highly valued in Chinese traditional medicine, protect against the life-threatening condition sepsis.Thu, 15 Nov 2012 13:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121115133312.htmStructure of enzyme topoisomerase II alpha unravelled providing basis for more accurate design of chemotherapeutic drugshttp://www.sciencedaily.com/releases/2012/11/121115132903.htm Medical researchers have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs. The type II topoisomerases are important enzymes that are involved in maintaining the structure of DNA and chromosome segregation during both replication and transcription of DNA. One of these enzymes, topoisomerase II alpha, is involved in the replication of DNA and cell proliferation, and is highly expressed in rapidly dividing cancer cells.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132903.htmNewly discovered enzyme important in the spreading of cancerhttp://www.sciencedaily.com/releases/2012/11/121115132901.htm Enzyme hunters at UiO have discovered the function of an enzyme that is important in the spreading of cancer. Cancer researchers now hope to inhibit the enzyme.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132901.htmGenetics point to serious pregnancy complication, pre-eclampsiahttp://www.sciencedaily.com/releases/2012/11/121115132613.htm New research has revealed a genetic link in pregnant moms - and their male partners - to pre-eclampsia, a life-threatening complication during pregnancy.Thu, 15 Nov 2012 13:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115132613.htmMolecular mechanisms underlying stem cell reprogramming decodedhttp://www.sciencedaily.com/releases/2012/11/121115132344.htm Thanks to some careful detective work, scientist better understand just how iPS cells form ? and why the Yamanaka process is inefficient, an important step to work out for regenerative medicine. The findings uncover cellular impediments to iPS cell development that, if overcome, could dramatically improve the efficiency and speed of iPS cell generation.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132344.htmSurprising genetic link between kidney defects and neurodevelopmental disorders in kidshttp://www.sciencedaily.com/releases/2012/11/121115132342.htm About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study has shown.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132342.htmEven moderate drinking in pregnancy can affect a child's IQhttp://www.sciencedaily.com/releases/2012/11/121114172833.htm Relatively small levels of exposure to alcohol while in the womb can influence a child's IQ, according to a new study using data from over 4,000 mothers and their children.Wed, 14 Nov 2012 17:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121114172833.htmGene nearly triples risk of Alzheimer's, international research team findshttp://www.sciencedaily.com/releases/2012/11/121114171710.htm A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team of researchers. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171710.htmDiscovery could lead to faster diagnosis for some chronic fatigue syndrome caseshttp://www.sciencedaily.com/releases/2012/11/121114171708.htm For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome - testing for antibodies linked to latent Epstein-Barr virus reactivation.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171708.htmResearch breakthrough could halt melanoma metastasis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121114153227.htm In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin.Wed, 14 Nov 2012 15:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114153227.htmPig genomes provide massive amount of genomic data for human healthhttp://www.sciencedaily.com/releases/2012/11/121114134512.htm Researchers provide a whole-genome sequence and analysis of number of pig breeds, including a miniature pig that serves a model for human medical studies and therapeutic drug testing.Wed, 14 Nov 2012 13:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121114134512.htmRare parasitic fungi could have anti-flammatory benefitshttp://www.sciencedaily.com/releases/2012/11/121114134054.htm Caterpillar fungi are rare parasites found on hibernating caterpillars in the mountains of Tibet. For centuries they have been highly prized as a traditional Chinese medicine - just a small amount can fetch hundreds of dollars.Wed, 14 Nov 2012 13:40:40 ESThttp://www.sciencedaily.com/releases/2012/11/121114134054.htmCancer therapy: Nanokey opens tumors to attackhttp://www.sciencedaily.com/releases/2012/11/121114113803.htm There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.Wed, 14 Nov 2012 11:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121114113803.htmHigh sperm DNA damage a leading cause of 'unexplained infertility', research findshttp://www.sciencedaily.com/releases/2012/11/121114113235.htm New research has uncovered the cause of infertility for 80 per cent of couples previously diagnosed with 'unexplained infertility': high sperm DNA damage.Wed, 14 Nov 2012 11:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114113235.htmA risk gene for cannabis psychosishttp://www.sciencedaily.com/releases/2012/11/121114083928.htm The ability of cannabis to produce psychosis has long been an important public health concern. This concern is growing in importance as there is emerging data that cannabis exposure during adolescence may increase the risk of developing schizophrenia, a serious psychotic disorder. Further, with the advent of medical marijuana, a new group of people with uncertain psychosis risk may be exposed to cannabis.Wed, 14 Nov 2012 08:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121114083928.htmBacterial DNA sequence used to map an infection outbreakhttp://www.sciencedaily.com/releases/2012/11/121113214635.htm For the first time, researchers have used DNA sequencing to help bring an infectious disease outbreak in a hospital to a close. Researchers used advanced DNA sequencing technologies to confirm the presence of an ongoing outbreak of methicillin-resistant Staphylococcus aureus (MRSA) in a Special Care Baby Unit in real time. This assisted in stopping the outbreak earlier, saving possible harm to patients. This approach is much more accurate than current methods used to detect hospital outbreaks.Tue, 13 Nov 2012 21:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121113214635.htmGenetic variation may modify associations between low vitamin D levels and adverse health outcomeshttp://www.sciencedaily.com/releases/2012/11/121113161506.htm Findings from a study suggest that certain variations in vitamin D metabolism genes may modify the association of low serum 25-hydroxyvitamin D concentrations with health outcomes such as hip fracture, heart attack, cancer, and death.Tue, 13 Nov 2012 16:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121113161506.htmNew type of bacterial protection found within cells: Novel immune system response to infections discoveredhttp://www.sciencedaily.com/releases/2012/11/121113143656.htm Biologists have discovered that fats within cells store a class of proteins with potent antibacterial activity, revealing a previously unknown type of immune system response that targets and kills bacterial infections.Tue, 13 Nov 2012 14:36:36 ESThttp://www.sciencedaily.com/releases/2012/11/121113143656.htmGlutamate neurotransmission system may be involved with depression riskhttp://www.sciencedaily.com/releases/2012/11/121113134807.htm Researchers using a new approach to identifying genes associated with depression have found that variants in a group of genes involved in transmission of signals by the neurotransmitter glutamate appear to increase the risk of depression.Tue, 13 Nov 2012 13:48:48 ESThttp://www.sciencedaily.com/releases/2012/11/121113134807.htmTargeting downstream proteins in cancer-causing pathway shows promise in cell, animal modelhttp://www.sciencedaily.com/releases/2012/11/121113134230.htm The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell?s powerhouse, making it dependent on the amino acid glutamine for survival. Depriving cells of glutamine selectively induces programmed cell death in cells overexpressing mutant Myc. Using Myc-active neuroblastoma cells, a team three priotein executors of the glutamine-starved cell, representing a downstream target at which to aim drugs. Roughly 25 percent of all neuroblastoma cases are associated with Myc-active cells.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134230.htmEven low-level radioactivity is damaging, scientists concludehttp://www.sciencedaily.com/releases/2012/11/121113134224.htm Even the very lowest levels of radiation are harmful to life, scientists have concluded, reporting the results of a wide-ranging analysis of 46 peer-reviewed studies published over the past 40 years. Variation in low-level, natural background radiation was found to have small, but highly statistically significant, negative effects on DNA as well as several measures of health.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134224.htmLoss of essential blood cell gene leads to anemiahttp://www.sciencedaily.com/releases/2012/11/121113122220.htm Scientists have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood. The findings promise to advance the biomedical community's understanding and treatment of human anemias and mitochondrial diseases, both known and unknown.Tue, 13 Nov 2012 12:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121113122220.htmWatching the developing brain, scientists glean clues on neurological disorderhttp://www.sciencedaily.com/releases/2012/11/121113122133.htm Researchers have tracked a gene's crucial role in orchestrating the placement of neurons in the developing brain. Their findings help unravel some of the mysteries of Joubert syndrome and other neurological disorders.Tue, 13 Nov 2012 12:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121113122133.htmSolving the mystery of aging: Longevity gene makes Hydra immortal and humans grow olderhttp://www.sciencedaily.com/releases/2012/11/121113091953.htm Why do we get older? When do we die and why? Is there a life without aging? For centuries, science has been fascinated by these questions. Now researchers have examined why the polyp Hydra is immortal -- and unexpectedly discovered a link to aging in humans.Tue, 13 Nov 2012 09:19:19 ESThttp://www.sciencedaily.com/releases/2012/11/121113091953.htmMen and women battle for ideal height: Evidence of an intralocus sexual conflict currently raging in human DNAhttp://www.sciencedaily.com/releases/2012/11/121113083536.htm A battle about the ideal height would appear to be raging in men's and women's genes. A researcher in Sweden has shown that this conflict is leading to a difference in reproductive success between men and women of varying height.Tue, 13 Nov 2012 08:35:35 ESThttp://www.sciencedaily.com/releases/2012/11/121113083536.htm

Source: http://www.sciencedaily.com/rss/health_medicine/genes.xml

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